The potential of 3D-FISH and super-resolution structured illumination microscopy for studies of 3D nuclear architecture: 3D structured illumination microscopy of defined chromosomal structures visualized by 3D (immuno)-FISH opens new perspectives for studies of nuclear architecture.

Markaki, Y; Smeets, D; Fiedler, S; Schmid, V; Schermelleh, L; Cremer, T; Cremer, M

Journal article

The potential of 3D-FISH and super-resolution structured illumination microscopy for studies of 3D nuclear architecture: 3D structured illumination microscopy of defined chromosomal structures visualized by 3D (immuno)-FISH opens new perspectives for studies of nuclear architecture.

Abstract:: Three-dimensional structured illumination microscopy (3D-SIM) has opened up new possibilities to study nuclear architecture at the ultrastructural level down to the ~100 nm range. We present first results and assess the potential using 3D-SIM in combination with 3D fluorescence in situ hybridization (3D-FISH) for the topographical analysis of defined nuclear targets. Our study also deals with the concern that artifacts produced by FISH may counteract the gain in resolution. We address the top...
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APA Style

Markaki, Y., Smeets, D., Fiedler, S., Schmid, V., Schermelleh, L., Cremer, T., & Cremer, M. (2012). The potential of 3D-FISH and super-resolution structured illumination microscopy for studies of 3D nuclear architecture: 3D structured illumination microscopy of defined chromosomal structures visualized by 3D (immuno)-FISH opens new perspectives for studies of nuclear architecture. BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology, 34(5), 412–426.

MLA Style

Markaki, Y., et al. “The Potential of 3D-FISH and Super-Resolution Structured Illumination Microscopy for Studies of 3D Nuclear Architecture: 3D Structured Illumination Microscopy of Defined Chromosomal Structures Visualized by 3D (Immuno)-FISH Opens New Perspectives for Studies of Nuclear Architecture.” BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology, vol. 34, no. 5, 2012, pp. 412–26.

Chicago Style

Markaki, Y, D Smeets, S Fiedler, V Schmid, L Schermelleh, T Cremer, and M Cremer. 2012. “The Potential of 3D-FISH and Super-Resolution Structured Illumination Microscopy for Studies of 3D Nuclear Architecture: 3D Structured Illumination Microscopy of Defined Chromosomal Structures Visualized by 3D (Immuno)-FISH Opens New Perspectives for Studies of Nuclear Architecture.” BioEssays : News and Reviews in Molecular, Cellular and Developmental Biology 34 (5): 412–26.
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