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Using the contribution matrix to evaluate complex study limitations in a network meta-analysis: a case study of bipolar maintenance pharmacotherapy review

Abstract:

Limitations in the primary studies constitute one important factor to be considered in the grading of recommendations assessment, development, and evaluation (GRADE) system of rating quality of evidence. However, in the network meta-analysis (NMA), such evaluation poses a special challenge because each network estimate receives different amounts of contributions from various studies via direct as well as indirect routes and because some biases have directions whose repercussion in the network...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1186/s13104-016-2019-1

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Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
Role:
Author
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Publisher:
BioMed Central Publisher's website
Journal:
BMC Research Notes Journal website
Volume:
9
Issue:
1
Pages:
218
Publication date:
2016-04-14
Acceptance date:
2016-03-31
DOI:
EISSN:
1756-0500
URN:
uuid:3eb16fa0-6651-4848-bc4e-550d7466bef6
Source identifiers:
616869
Local pid:
pubs:616869

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