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Journal article

Limited polymorphism of the Kelch propeller domain in P. malariae and P. ovale isolates from Thailand.

Abstract:

Artemisinin resistance in P. falciparum, the agent of severe malaria, is currently a major obstacle to malaria control in southeast Asia. The gene named “kelch13” has been associated with artemisinin resistance in P. falciparum. The orthologue of the kelch gene in P. vivax has been identified and a small number of mutations found in previous studies. The kelch orthologues in the other two human malaria parasites, P. malariae and P. ovale, have not yet been studied. Therefore, in this study, t...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1128/AAC.00138-16

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
Wellcome Trust More from this funder
Mahidol University More from this funder
Publisher:
American Society for Microbiology Publisher's website
Journal:
Antimicrobial Agents and Chemotherapy Journal website
Volume:
60
Issue:
7
Pages:
4055-4062
Publication date:
2016-04-01
DOI:
EISSN:
1098-6596
ISSN:
0066-4804
Language:
English
Keywords:
Pubs id:
pubs:619879
UUID:
uuid:3eac4a59-9898-4ad9-8258-ca1f99b55d06
Local pid:
pubs:619879
Source identifiers:
619879
Deposit date:
2016-05-12

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