- Abstract:
- 1,5-Dideoxy-1,5-imino-L-fucitol (1), synthesised from methyl α-D-glucopyranoside, is a potent competitive inhibitor of the hydrolysis of p-nitrophenyl α-L-fucopyranoside catalysed by α-L-fucosidase (ex. bovine epididymis) causing 50% inhibition of enzymic activity at 2.5 × 10 -8 M.
- Publication status:
- Published
- Publisher copy:
- 10.1039/c39850000841
-
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- Journal:
- JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS
- Issue:
- 13
- Pages:
- 841-842
- Publication date:
- 1985
- DOI:
- ISSN:
-
0022-4936
- URN:
-
uuid:3eaa444b-91d2-4fdc-a8bc-47de8ca32b0d
- Source identifiers:
-
42508
- Local pid:
- pubs:42508
- Language:
- English
- Copyright date:
- 1985
Journal article
SYNTHESIS FROM D-GLUCOSE OF 1,5-DIDEOXY-1,5-IMINO-L-FUCITOL, A POTENT ALPHA-L-FUCOSIDASE INHIBITOR
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