The role of donor-specific HLA alloantibodies in liver transplantation.

Journal article

The impact of donor-specific HLA alloantibodies (DSA) on short- and long-term liver transplant outcome is not clearly defined. While it is clear that not all levels of allosensitization produce overt clinical injury, and that liver allografts possess some degree of alloantibody resistance, alloantibody-mediated adverse consequences are increasingly being recognized. To better define the current state of this topic, we assembled experts to provide insights, explore controversies and develop re...

Expand abstract

Authors: O'Leary, J; Demetris, A; Friedman, L; Gebel, H; Halloran, P

• Publication status: Published
• Publisher: Blackwell Publishing Ltd
• Journal: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
• Volume: 14
• Issue: 4
• Pages: 779-787
• Publication date: 2014-04-01
• DOI: 10.1111/ajt.12667
• EISSN: 1600-6143
• ISSN: 1600-6135
• Language: English
• Keywords: Graft Rejection; Prognosis; HLA Antigens; Humans; Liver Diseases; Isoantibodies; Tissue Donors; Liver Transplantation; Research Report; Practice Guidelines as Topic