Journal article icon

Journal article

RelB/p50 regulates TNF production in LPS-stimulated dendritic cells and macrophages.

Abstract:

Dendritic cells (DCs) and macrophages are effective antigen-presenting cells, and DCs, once matured, have the ability to potently activate naïve T cells. While the canonical p65/p50 NF-κB pathway seems to have an important role during LPS-stimulation of these cells, the specific contribution of the non-canonical RelB/p50 subunits is not clear yet. We aimed to investigate the relevance of this pathway in DCs and macrophages by using replication-deficient adenoviruses overexpressing RelB and p5...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1016/j.cyto.2012.12.029

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Role:
Author
Journal:
Cytokine
Volume:
61
Issue:
3
Pages:
736-740
Publication date:
2013-03-05
DOI:
EISSN:
1096-0023
ISSN:
1043-4666
URN:
uuid:3e919a85-bc66-4774-8897-c0f67e7f38c7
Source identifiers:
384217
Local pid:
pubs:384217

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP