Journal article
A model system to explore the detection limits of antibody-based immuno-SPECT imaging of exclusively intranuclear epitopes
- Abstract:
-
PURPOSE: Imaging of intranuclear epitopes using antibodies tagged to cell penetrating peptides (CPPs) has great potential given its versatility, specificity and sensitivity. However, this process is technically challenging because of the location of the target. Previous research has demonstrated a variety of intranuclear epitopes that can be targeted with antibody-based radioimmunoconjugates (RICs). Here, we developed a controlled expression model of nuclear localised GFP to interrogate the t...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
Bibliographic Details
- Publisher:
- Society of Nuclear Medicine Publisher's website
- Journal:
- Journal of Nuclear Medicine Journal website
- Volume:
- 62
- Issue:
- 11
- Pages:
- 1537-1544
- Publication date:
- 2021-03-31
- Acceptance date:
- 2021-02-02
- DOI:
- EISSN:
-
2159-662X
- ISSN:
-
0161-5505
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
1159836
- Local pid:
- pubs:1159836
- Deposit date:
- 2021-02-02
Terms of use
- Copyright holder:
- Veal et al.
- Copyright date:
- 2021
- Rights statement:
- Copyright © 2021 The Author(s). This is an open access article published under CC BY 4.0.
- Licence:
- CC Attribution (CC BY)
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