- Abstract:
-
A conserved repeated epitope, (NANP)3, of the circumsporozoite protein of Plasmodium falciparum has been identified previously as a putative target for artificially induced immunity to malaria. We examined the role of humoral responses to this epitope in acquired immunity to malaria in a rural African population. Seropositivity to (NANP)3 was slow to develop (9% positive in subjects aged 1-11 years; 88% in those of 30 years and above), and responses in younger subjects were transient. The poo...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/0035-9203(88)90495-6
-
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- Journal:
- Transactions of the Royal Society of Tropical Medicine and Hygiene
- Volume:
- 82
- Issue:
- 4
- Pages:
- 532-537
- Publication date:
- 1988-01-01
- DOI:
- EISSN:
-
1878-3503
- ISSN:
-
0035-9203
- URN:
-
uuid:3e8841b6-452a-4d4e-ab1d-c1e3901302ec
- Source identifiers:
-
184973
- Local pid:
- pubs:184973
- Copyright date:
- 1988
Journal article
Anti-sporozoite antibodies and immunity to malaria in a rural Gambian population.
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