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Journal article

The pathophysiology of the intervertebral disk

Abstract:

After a review of disk structure, the pivotal role of disk cells in producing and renewing the extracellular disk matrix is emphasized. Disk cells nutrition rely on nutrients that diffuse through the vertebral endplates. Microelectrode methods have been developed to study nutrient diffusion and endplate permeability. Mechanical stimuli modify disk cell activity. Scoliosis is associated with decreased endplate permeability, a factor that may play a role in disk degeneration and scoliosis progr...

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Journal:
Revue du Rhumatisme (Edition Francaise)
Volume:
68
Issue:
10-11
Pages:
903-907
Publication date:
2001-11-05
DOI:
ISSN:
1169-8330
URN:
uuid:3e87f31d-5a27-4aee-81d9-fe0f731b7ca8
Source identifiers:
238030
Local pid:
pubs:238030

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