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Journal article

Effects of MACPF/CDC proteins on lipid membranes

Abstract:

Recent work on the MACPF/CDC superfamily of pore-forming proteins has focused on the structural analysis of monomers and pore-forming oligomeric complexes. We set the family of proteins in context and highlight aspects of their function which the direct and exclusive equation of oligomers with pores fails to explain. Starting with a description of the distribution of MACPF/CDC proteins across the domains of life, we proceed to show how their evolutionary relationships can be understood on the...

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Publisher copy:
10.1007/s00018-012-1153-8

Authors


Journal:
Cellular and Molecular Life Sciences
Volume:
70
Issue:
12
Pages:
2083-2098
Publication date:
2013-06-05
DOI:
EISSN:
1420-9071
ISSN:
1420-682X
URN:
uuid:3e83921b-6664-479d-97fb-bb34ef9f79e4
Source identifiers:
405704
Local pid:
pubs:405704

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