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Risperidone augmentation decreases rapid eye movement sleep and decreases wake in treatment-resistant depressed patients.

Abstract:

BACKGROUND: The atypical antipsychotic agent risperidone has beneficial effects on mood in patients with schizophrenia. This study aimed to assess whether risperidone produced typical antidepressant-like effects in the polysomnogram of healthy subjects and in depressed patients unresponsive to antidepressant medication. METHOD: We measured the effect of a single dose of risperidone (1 mg) on the polysomnogram of 8 healthy volunteers in a placebo-controlled, double-blind, crossover design. We...

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Publication status:
Published

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Publisher copy:
10.4088/JCP.v64n0212

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Journal:
Journal of clinical psychiatry
Volume:
64
Issue:
2
Pages:
192-196
Publication date:
2003-02-01
DOI:
EISSN:
1555-2101
ISSN:
0160-6689
Source identifiers:
185784

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