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Host phylogeny determines viral persistence and replication in novel hosts.

Abstract:

Pathogens switching to new hosts can result in the emergence of new infectious diseases, and determining which species are likely to be sources of such host shifts is essential to understanding disease threats to both humans and wildlife. However, the factors that determine whether a pathogen can infect a novel host are poorly understood. We have examined the ability of three host-specific RNA-viruses (Drosophila sigma viruses from the family Rhabdoviridae) to persist and replicate in 51 diff...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1371/journal.ppat.1002260

Authors


Longdon, B More by this author
Hadfield, JD More by this author
Webster, CL More by this author
Obbard, DJ More by this author
Jiggins, FM More by this author
Publisher:
Public Library of Science Publisher's website
Journal:
PLoS pathogens Journal website
Volume:
7
Issue:
9
Pages:
e1002260
Publication date:
2011-09-05
DOI:
EISSN:
1553-7374
ISSN:
1553-7366
URN:
uuid:3e82d63d-ef45-4816-8e75-273db115862e
Source identifiers:
252072
Local pid:
pubs:252072

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