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Effect of lengthening rate on angiogenesis during distraction osteogenesis.

Abstract:

This study investigated the angiogenic response to four varying rates (0.3, 0.7, 1.3, and 2.7 mm/day) of distraction in a rabbit model of leg-lengthening. Immunostaining was performed with use of specific antibodies to type-IV collagen and endothelial cell antigen to examine semiquantitatively the presence of blood vessels in the developing tissues. With use of the Chalkley counting method, the greatest number of positive-staining blood vessel cells was found in the central fibrous zone of th...

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Publication status:
Published

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Publisher copy:
10.1002/jor.1100170310

Authors


Simpson, AH More by this author
Kenwright, J More by this author
Triffitt, JT More by this author
Publisher:
J Bone Jt Surgery Inc.
Journal:
Journal of orthopaedic research : official publication of the Orthopaedic Research Society
Volume:
17
Issue:
3
Pages:
362-367
Publication date:
1999-05-05
DOI:
EISSN:
1554-527X
ISSN:
0736-0266
URN:
uuid:3e49a345-cc0f-4f30-9c96-9fba104b296b
Source identifiers:
108339
Local pid:
pubs:108339

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