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96 The effect of ramipril on the rate of aortic dilatation in bicuspid aortic valve disease: results from a prospective, double blinded, randomised trial.

Abstract:

INTRODUCTION: Dilation of the ascending aorta (AA) is associated with bicuspid aortic valve (BAV) disease and currently no medical therapy exists to delay or prevent AA dilatation in these patients. Inhibition of the renin-angiotensin system (RAS) appears toslow the rate of aortic dilatation in Marfan syndrome, but the effect on the aorta in BAV disease is unknown.We hypothesised that inhibition of the RAS in patients with BAV may reduce the rate of AA dilatation. METHODS: This was a sub stud...

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Authors


Francis, J More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Cardiovascular Medicine
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Volume:
100 Suppl 3
Issue:
Suppl 3
Pages:
A56
Publication date:
2014-06-05
DOI:
EISSN:
1468-201X
ISSN:
1355-6037
URN:
uuid:3e19ecfb-720b-4a37-9bfa-46ee0c9c7b72
Source identifiers:
469478
Local pid:
pubs:469478

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