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96 The effect of ramipril on the rate of aortic dilatation in bicuspid aortic valve disease: results from a prospective, double blinded, randomised trial.

Abstract:

INTRODUCTION: Dilation of the ascending aorta (AA) is associated with bicuspid aortic valve (BAV) disease and currently no medical therapy exists to delay or prevent AA dilatation in these patients. Inhibition of the renin-angiotensin system (RAS) appears toslow the rate of aortic dilatation in Marfan syndrome, but the effect on the aorta in BAV disease is unknown.We hypothesised that inhibition of the RAS in patients with BAV may reduce the rate of AA dilatation. METHODS: This was a sub stud...

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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author
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Volume:
100 Suppl 3
Issue:
Suppl 3
Pages:
A56
Host title:
Heart (British Cardiac Society)
Publication date:
2014-06-01
Event location:
England
DOI:
EISSN:
1468-201X
ISSN:
1355-6037
Source identifiers:
469478
Keywords:
Pubs id:
pubs:469478
UUID:
uuid:3e19ecfb-720b-4a37-9bfa-46ee0c9c7b72
Local pid:
pubs:469478
Deposit date:
2014-08-22

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