- Abstract:
-
Microsatellite instability has been reported in a wide variety of cancer types. Inactivation or loss of tumour suppressor genes has been shown to result in cell cycle deregulation and neoplastic growth. We conducted a microsatellite study using fluorescent-based DNA technology to determine whether mutations in the microsatellite sequences of the deleted in colorectal cancer (DCC) gene, a tumour suppressor at 18q21.1, have any pathologic correlation or prognostic significance in nephroblastoma...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1038/modpathol.3800022
-
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- Journal:
- MODERN PATHOLOGY
- Volume:
- 17
- Issue:
- 1
- Pages:
- 89-95
- Publication date:
- 2004-01-05
- DOI:
- EISSN:
-
1530-0285
- ISSN:
-
0893-3952
- URN:
-
uuid:3df5d909-1774-4f59-8774-a00609fcede9
- Source identifiers:
-
122165
- Local pid:
- pubs:122165
- Language:
- English
- Keywords:
- Copyright date:
- 2004
Journal article
Microsatellite analysis of the DCC gene in nephroblastomas: pathologic correlations and prognostic implications
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