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Journal article

Progress in our understanding of the pathogenesis of ankylosing spondylitis

Abstract:

AS is a common rheumatic condition characterized by inflammation and new bone formation. The pathogenesis of AS is likely multifactorial and has not been fully elucidated to date. A major genetic role has been demonstrated. The strongest genetic association is with HLA B27. Numerous other associated genetic polymorphisms have been identified, including those affecting the type 17 immune pathway, although the precise link between genetics and pathogenesis remains unexplained. Several immunolog...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1093/rheumatology/key001

Authors


More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS
Subgroup:
Botnar Research Centre
Publisher:
Oxford University Press Publisher's website
Journal:
Rheumatology Journal website
Volume:
57
Issue:
S6
Pages:
vi4-vi9
Publication date:
2018-11-16
DOI:
EISSN:
1462-0332
ISSN:
1462-0324
Pubs id:
pubs:945341
URN:
uri:3df0cbe3-d261-4242-b238-528fc6bbca40
UUID:
uuid:3df0cbe3-d261-4242-b238-528fc6bbca40
Local pid:
pubs:945341

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