Journal article
Progress in our understanding of the pathogenesis of ankylosing spondylitis
- Abstract:
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AS is a common rheumatic condition characterized by inflammation and new bone formation. The pathogenesis of AS is likely multifactorial and has not been fully elucidated to date. A major genetic role has been demonstrated. The strongest genetic association is with HLA B27. Numerous other associated genetic polymorphisms have been identified, including those affecting the type 17 immune pathway, although the precise link between genetics and pathogenesis remains unexplained. Several immunolog...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
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- Files:
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(pdf, 269.4KB)
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- Publisher copy:
- 10.1093/rheumatology/key001
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Authors
Bibliographic Details
- Publisher:
- Oxford University Press Publisher's website
- Journal:
- Rheumatology Journal website
- Volume:
- 57
- Issue:
- S6
- Pages:
- vi4-vi9
- Publication date:
- 2018-11-16
- DOI:
- EISSN:
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1462-0332
- ISSN:
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1462-0324
- Pubs id:
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pubs:945341
- URN:
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uri:3df0cbe3-d261-4242-b238-528fc6bbca40
- UUID:
-
uuid:3df0cbe3-d261-4242-b238-528fc6bbca40
- Local pid:
- pubs:945341
Item Description
- Language:
- English
- Keywords:
Terms of use
- Copyright holder:
- Simone et al.
- Copyright date:
- 2018
- Notes:
-
Copyright © 2018 The Authors. Published by Oxford University Press on behalf of the British Society for Rheumatology.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
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