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Mechanobiology of bone healing and regeneration: In vivo models

Abstract:

Mechanical boundary conditions are well known to influence the regeneration of bone and mechanobiology is the study of how mechanical or physical stimuli regulate biological processes. In vivo models have been applied over many years to investigate the effects of mechanics on bone healing. Early models have focused on the influence of mechanical stability on healing outcome, with an interest in parameters such as the magnitude of interfragmentary movement, the rate and timing of application o...

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Publication status:
Published

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Publisher copy:
10.1243/09544119JEIM808

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Role:
Author
Journal:
Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine
Volume:
224
Issue:
12
Pages:
1543-1553
Publication date:
2010-12-01
DOI:
EISSN:
2041-3033
ISSN:
0954-4119
Pubs id:
pubs:344596
UUID:
uuid:3de03bbb-34bb-4cc5-8359-338fe7177a32
Local pid:
pubs:344596
Source identifiers:
344596
Deposit date:
2013-11-16

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