Journal article
DNA modifications: naturally more error prone?
- Abstract:
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Epigenetic DNA modifications are essential for normal cell function in vertebrates, but they can also be hotspots of mutagenesis. Methylcytosine in particular has long been known to be less stable than other nucleotides and spontaneously deaminates to thymine. Beyond this well-established phenomenon, however, the influence of epigenetic marks on mutagenesis has recently become an active field of investigation. In this review, we summarize current knowledge of the interactions between differen...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Accepted Manuscript
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(pdf, 319.2KB)
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- Publisher copy:
- 10.1016/j.tig.2018.04.005
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Authors
Funding
Ludwig Cancer Research
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Bibliographic Details
- Publisher:
- Cell Press Publisher's website
- Journal:
- Trends in Genetics Journal website
- Volume:
- 34
- Issue:
- 8
- Pages:
- 627-638
- Publication date:
- 2018-05-28
- Acceptance date:
- 2018-04-27
- DOI:
- ISSN:
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0168-9525
- Pubs id:
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pubs:854222
- URN:
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uri:3db919f8-074a-480b-abb9-3977005f8a93
- UUID:
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uuid:3db919f8-074a-480b-abb9-3977005f8a93
- Local pid:
- pubs:854222
Item Description
Terms of use
- Copyright holder:
- Elsevier Ltd
- Copyright date:
- 2018
- Notes:
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Copyright © 2018 Elsevier Ltd. This is the accepted manuscript version of the article. The final version is available online from Elsevier at: https://doi.org/10.1016/j.tig.2018.04.005
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