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Genetics of chronic otitis media: a mouse to man approach

Abstract:

Chronic otitis media (OM) is an archetypal complex disease, which is particularly prevalent in childhood. Epidemiological data suggest high heritability for disease susceptibility, but previous genetic association studies have had methodological flaws, and none have specifically focused on chronic OM phenotypes.

Mouse models represent one way to ascertain candidate loci for human association testing. A number of mouse models of middle ear inflammation have been reported, but many s...

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Institution:
University of Oxford
Oxford college:
Balliol College
Department:
Medical Sciences Division - Surgery
Role:
Author

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Role:
Supervisor
Role:
Supervisor
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Funding agency for:
Mahmood F Bhutta
Publication date:
2012
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
URN:
uuid:3dacb68a-414c-4a79-bea4-c639cc01c0ff
Local pid:
ora:7091

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