Synthesis and phytotoxic activity of new pyridones derived from 4-hydroxy-6-methylpyridin-2(1H)-one
Commercial dehydroacetoc acid was converted into 4-hydroxy-6-methylpyridin-2(1H)-one (3), which was then condensed with several aliphatic aldehydes to produce seven new title compounds in variable yields (35-92%). Reaction of 3 with α,β-unsaturated aldehydes resulted in the formation of condensed pyran derivatives 4g' and 4h'. A mechanism is proposed to explain the formation of such compounds. The effects of all methylpyridin-2(1H)-one derivatives on the development of the dicotyledonous spec...Expand abstract
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Citation: Demuner, A. J. et al. (2009). 'Synthesis and phytotoxic activity of new pyridones derived from 4-hydroxy-6-methylpyridin-2(1H)-one', Molecules 14(12), 4973-4986. [Available at http://www.mdpi.com/journal/molecules]. © 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.
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