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Synthesis and phytotoxic activity of new pyridones derived from 4-hydroxy-6-methylpyridin-2(1H)-one

Abstract:

Commercial dehydroacetoc acid was converted into 4-hydroxy-6-methylpyridin-2(1H)-one (3), which was then condensed with several aliphatic aldehydes to produce seven new title compounds in variable yields (35-92%). Reaction of 3 with α,β-unsaturated aldehydes resulted in the formation of condensed pyran derivatives 4g' and 4h'. A mechanism is proposed to explain the formation of such compounds. The effects of all methylpyridin-2(1H)-one derivatives on the development of the dicotyledonous spec...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.3390/molecules14124973

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Institution:
Federal University of Vicosa, Brazil
Department:
Department of Chemistry
Role:
Author
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Institution:
Federal University of Vicosa, Brazil
Department:
Department of Chemistry
Role:
Author
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Institution:
"Federal University of Vicosa, Brazil", "University of Oxford"
Department:
Department of Chemistry
Role:
Author
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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author
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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author
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Publisher:
Molecular Diversity Preservation International (MDPI) Publisher's website
Journal:
Molecules Journal website
Volume:
14
Issue:
12
Pages:
4973-4986
Publication date:
2009-01-01
DOI:
ISSN:
1420-3049
Language:
English
Keywords:
Subjects:
UUID:
uuid:3da8a536-2f55-4898-ba89-5057757eaf10
Local pid:
ora:5093
Deposit date:
2011-03-09

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