- Abstract:
-
HIV-specific CTL play a central role in immune control of HIV. The basis for understanding the success or failure of this immune response requires identification of the specific epitopes targeted by CTL. However, in populations most severely affected by the global epidemic, this fundamental knowledge is hindered by the lack of characterization of many of the HLA class I alleles highly prevalent in such populations. Overall, the peptide-binding motif has been determined for a small minority (9...
Expand abstract - Publisher copy:
- 10.4049/jimmunol.176.8.4699
-
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- Journal:
- Journal of immunology (Baltimore, Md. : 1950)
- Volume:
- 176
- Issue:
- 8
- Pages:
- 4699-4705
- Publication date:
- 2006-04-05
- DOI:
- EISSN:
-
1550-6606
- ISSN:
-
0022-1767
- URN:
-
uuid:3d97f1fb-6647-49d6-85cc-7ce9acd5d05d
- Source identifiers:
-
191146
- Local pid:
- pubs:191146
- Copyright date:
- 2006
Journal article
Motif inference reveals optimal CTL epitopes presented by HLA class I alleles highly prevalent in southern Africa.
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