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Journal article

Impact of amoxicillin therapy on resistance selection in patients with community-acquired lower respiratory tract infections: a randomized, placebo-controlled study.

Abstract:

Objectives

To determine the effect of amoxicillin treatment on resistance selection in patients with community-acquired lower respiratory tract infections in a randomized, placebo-controlled trial.

Methods

Patients were prescribed amoxicillin 1 g, three times daily (n=52) or placebo (n=50) for 7 days. Oropharyngeal swabs obtained before, within 48 h post-treatment and at 28–35 days were assessed for proportions of amoxicillin-resistant (ARS; amoxicillin MIC ≥2 mg/...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1093/jac/dkw234

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Publisher:
Oxford University Press Publisher's website
Journal:
Journal of Antimicrobial Chemotherapy Journal website
Volume:
71
Issue:
11
Pages:
3258-3267
Publication date:
2016-06-05
Acceptance date:
2016-05-16
DOI:
EISSN:
1460-2091
ISSN:
0305-7453
Pubs id:
pubs:632247
URN:
uri:3d4e1c2c-d839-4cd9-b2a1-27a537b1198c
UUID:
uuid:3d4e1c2c-d839-4cd9-b2a1-27a537b1198c
Local pid:
pubs:632247

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