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Journal article

Inflammatory bowel disease and colon cancer.

Abstract:

The inflammatory bowel diseases (IBD); Crohn's and Ulcerative colitis, result from an altered host response to intestinal flora. Recurrent inflammation with ulceration and tissue restitution confers an increased risk of cancer in both UC and Crohns, and genome wide searches have identified a number of disease susceptibility alleles. The carcinogenesis pathway in colitis-associated colorectal cancer (CACRC) is less clearly understood than it's sporadic counterpart. Clonal ordering experiments ...

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Publication status:
Published

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Publisher copy:
10.1007/978-3-642-03503-6_6

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Role:
Author
Journal:
Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer
Volume:
185
Pages:
99-115
Publication date:
2011-01-01
DOI:
ISSN:
0080-0015
Source identifiers:
313758
Language:
English
Keywords:
Pubs id:
pubs:313758
UUID:
uuid:3d24853a-8d4a-4f1b-812e-a4b29d8eb070
Local pid:
pubs:313758
Deposit date:
2012-12-19

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