Journal article
Determinants of primaquine and carboxyprimaquine exposures in children and adults with Plasmodium vivax malaria
- Abstract:
-
Background Primaquine is the only widely available drug for radical cure of Plasmodium vivax malaria. There is uncertainty whether the pharmacokinetic properties of primaquine are altered significantly in childhood or not.
Methods Glucose-6-phosphate dehydrogenase normal patients with uncomplicated P. vivax malaria were randomized to receive either chloroquine (25mg base/kg) or dihydroartemisinin-piperaquine (dihydroartemisinin 7mg/kg and piperaquine 55m... Expand abstract
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Authors
Bibliographic Details
- Publisher:
- American Society for Microbiology Publisher's website
- Journal:
- Antimicrobial Agents and Chemotherapy Journal website
- Volume:
- 65
- Issue:
- 11
- Article number:
- e01302-21
- Publication date:
- 2021-08-16
- Acceptance date:
- 2021-08-11
- DOI:
- EISSN:
-
1098-6596
- ISSN:
-
0066-4804
- Pmid:
-
34398667
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
1191318
- Local pid:
- pubs:1191318
- Deposit date:
- 2021-08-30
Terms of use
- Copyright holder:
- Chu et al.
- Copyright date:
- 2021
- Rights statement:
- © Chu et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License.
- Notes:
- This is the accepted manuscript version of the article. The final version is available from the American Society for Microbiology at https://doi.org/10.1128/AAC.01302-21
- Licence:
- CC Attribution (CC BY)
Metrics
If you are the owner of this record, you can report an update to it here: Report update to this record