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Increased in-stent stenosis in ApoE knockout mice: insights from a novel mouse model of balloon angioplasty and stenting.

Abstract:

OBJECTIVE: We aimed to develop and validate a model of angioplasty and stenting in mice that would allow investigation of the response to stent injury using genetically modified mouse strains. METHODS AND RESULTS: Aortic segments from either C57BL/6 wild-type or atherosclerotic ApoE-KO mice underwent balloon angioplasty alone or balloon angioplasty and stenting with a 1.25x2.5 mm stainless steel stent. Vessels were carotid-interposition grafted into genetically identical littermate recipient...

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Publication status:
Published

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Authors


Bannister, T More by this author
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Journal:
Arteriosclerosis, thrombosis, and vascular biology
Volume:
27
Issue:
4
Pages:
833-840
Publication date:
2007-04-05
DOI:
EISSN:
1524-4636
ISSN:
1079-5642
URN:
uuid:3d05acf5-0767-4925-9de2-e1deeac92d35
Source identifiers:
26840
Local pid:
pubs:26840

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