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Induction of transplantation tolerance through regulatory cells: from mice to men.

Abstract:

Organ transplantation results in the activation of both innate and adaptive immune responses to the foreign antigens. While these responses can be limited with the use of systemic immunosuppressants, the induction of regulatory cell populations may be a novel strategy for the maintenance of specific immunological unresponsiveness that can reduce the severity of the detrimental side effects of current therapies. Our group has extensively researched different regulatory T-cell induction protoco...

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Publication status:
Published

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Publisher copy:
10.1111/imr.12158

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Surgical Sciences
Role:
Author
Journal:
Immunological reviews
Volume:
258
Issue:
1
Pages:
102-116
Publication date:
2014-03-01
DOI:
EISSN:
1600-065X
ISSN:
0105-2896
Source identifiers:
450287
Language:
English
Keywords:
Pubs id:
pubs:450287
UUID:
uuid:3d031bb9-fc71-4354-8a86-47cc748ddbea
Local pid:
pubs:450287
Deposit date:
2014-05-09

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