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Nonlinear modeling of the dynamic effects of arterial pressure and CO2 variations on cerebral blood flow in healthy humans.

Abstract:

The effect of spontaneous beat-to-beat mean arterial blood pressure fluctuations and breath-to-breath end-tidal CO2 fluctuations on beat-to-beat cerebral blood flow velocity variations is studied using the Laguerre-Volterra network methodology for multiple-input nonlinear systems. The observations made from experimental measurements from ten healthy human subjects reveal that, whereas pressure fluctuations explain most of the high-frequency blood flow velocity variations (above 0.04 Hz), end-...

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Publication status:
Published

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Publisher copy:
10.1109/tbme.2004.834272

Authors


Mitsis, GD More by this author
Poulin, MJ More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Marmarelis, VZ More by this author
Journal:
IEEE transactions on bio-medical engineering
Volume:
51
Issue:
11
Pages:
1932-1943
Publication date:
2004-11-05
DOI:
EISSN:
1558-2531
ISSN:
0018-9294
URN:
uuid:3cea02ae-e3c3-4a3f-aa02-db7bbd4a3482
Source identifiers:
114630
Local pid:
pubs:114630

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