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Journal article

JNK signaling: Regulation and functions based on complex protein-protein partnerships

Abstract:

The c-Jun N-terminal kinases (JNKs), as members of the mitogen-activated protein kinase (MAPK) family, mediate eukaryotic cell responses to a wide range of abiotic and biotic stress insults. JNKs also regulate important physiological processes, including neuronal functions, immunological actions, and embryonic development, via their impact on gene expression, cytoskeletal protein dynamics, and cell death/survival pathways. Although the JNK pathway has been under study for >20 years, its co...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1128/MMBR.00043-14

Authors


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Institution:
University of Oxford
Division:
MPLS Division
Department:
Chemistry
Sub department:
Organic Chemistry
Department:
Unknown
Role:
Author
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Role:
Author
ORCID:
0000-0002-8345-1311
More by this author
Role:
Author
ORCID:
0000-0001-9745-3716
Publisher:
American Society for Microbiology Journals Publisher's website
Journal:
Microbiology and Molecular Biology Reviews Journal website
Volume:
80
Issue:
3
Pages:
793-835
Publication date:
2016-07-27
Acceptance date:
2016-07-01
DOI:
EISSN:
1098-5557
ISSN:
1092-2172
Pmid:
27466283
Language:
English
Keywords:
Pubs id:
pubs:1065139
UUID:
uuid:3ccbdca8-7174-44dd-96db-8e660beb0244
Local pid:
pubs:1065139
Source identifiers:
1065139
Deposit date:
2019-10-30

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