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PAX6 mutation in association with ptosis, cataract, iris hypoplasia, corneal opacification and diabetes: a new variant of familial aniridia?

Abstract:

BACKGROUND: We report a family with ptosis, cataract, iris hypoplasia and gradual corneal opacification occurring in association with a PAX6 mutation. DESIGN: Case-series. PARTICIPANTS: Fourteen family members - 8 affected, 6 unaffected controls. METHODS: All participants underwent ophthalmological assessment, including best-corrected visual acuity, slit-lamp-examination, pachymetry, endothelial cell-count, tonometry and dilated fundoscopy. All subjects underwent anthropometry and assessment ...

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Publication status:
Published

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Publisher copy:
10.1111/ceo.12109

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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
OCDEM
Role:
Author
Journal:
Clinical and experimental ophthalmology
Volume:
41
Issue:
9
Pages:
835-841
Publication date:
2013-12-01
DOI:
EISSN:
1442-9071
ISSN:
1442-6404
Language:
English
Keywords:
Pubs id:
pubs:394887
UUID:
uuid:3cc642df-4110-4165-a253-be29367fa72c
Local pid:
pubs:394887
Source identifiers:
394887
Deposit date:
2013-11-17

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