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Expression profiling of repetitive elements by melting temperature analysis: variation in HERV-W gag expression across human individuals and tissues.

Abstract:

BACKGROUND: Human endogenous retroviruses (HERV) constitute approximately 8% of the human genome and have long been considered "junk". The sheer number and repetitive nature of these elements make studies of their expression methodologically challenging. Hence, little is known of transcription of genomic regions harboring such elements. RESULTS: Applying a recently developed technique for obtaining high resolution melting temperature data, we examined the frequency distributions of HERV-W ga...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1186/1471-2164-10-532

Authors


Stanley Medical Research Institute More from this funder
Stiftelsen Lars Hiertas Minne More from this funder
Swedish Brain Foundation More from this funder
Publisher:
BioMed Central Publisher's website
Journal:
BMC genomics Journal website
Volume:
10
Issue:
1
Pages:
Article no. 532
Publication date:
2009-01-01
DOI:
EISSN:
1471-2164
ISSN:
1471-2164
Source identifiers:
344392

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