- Abstract:
-
alpha-Cells were identified in preparations of dispersed mouse islets by immunofluorescence microscopy. A high fraction of alpha-cells correlated with a small cell size measured as the average cell diameter (10 microm) and whole-cell capacitance (<4 pF). The alpha-cells generated action potentials at a low frequency (1 Hz) in the absence of glucose. These action potentials were reversibly inhibited by elevation of the glucose concentration to 20 mmol/l. The action potentials originated fro...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.2337/diabetes.49.9.1500
-
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- Journal:
- Diabetes
- Volume:
- 49
- Issue:
- 9
- Pages:
- 1500-1510
- Publication date:
- 2000-09-05
- DOI:
- EISSN:
-
1939-327X
- ISSN:
-
0012-1797
- URN:
-
uuid:3ca35771-2ccb-4597-89f5-0898cc3972de
- Source identifiers:
-
23395
- Local pid:
- pubs:23395
- Copyright date:
- 2000
Journal article
Tight coupling between electrical activity and exocytosis in mouse glucagon-secreting alpha-cells.
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