- Abstract:
-
Remote ischemic preconditioning reduces myocardial infarction (MI) in animal models. We tested the hypothesis that the systemic protection thus induced is effective when ischemic preconditioning is administered during ischemia (PerC) and before reperfusion and examined the role of the K(+)-dependent ATP (K(ATP)) channel. Twenty 20-kg pigs were randomized (10 in each group) to 40 min of left anterior descending coronary artery occlusion with 120 min of reperfusion. PerC consisted of four 5-min...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1152/ajpheart.00617.2006
-
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- Journal:
- American journal of physiology. Heart and circulatory physiology
- Volume:
- 292
- Issue:
- 4
- Pages:
- H1883-H1890
- Publication date:
- 2007-04-05
- DOI:
- EISSN:
-
1522-1539
- ISSN:
-
0363-6135
- URN:
-
uuid:3c9be6fd-9170-4ab8-919f-d27a5254ca0d
- Source identifiers:
-
105151
- Local pid:
- pubs:105151
- Language:
- English
- Keywords:
- Copyright date:
- 2007
Journal article
Intermittent peripheral tissue ischemia during coronary ischemia reduces myocardial infarction through a KATP-dependent mechanism: first demonstration of remote ischemic perconditioning.
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