Journal article
Intermittent peripheral tissue ischemia during coronary ischemia reduces myocardial infarction through a KATP-dependent mechanism: first demonstration of remote ischemic perconditioning.
- Abstract:
-
Remote ischemic preconditioning reduces myocardial infarction (MI) in animal models. We tested the hypothesis that the systemic protection thus induced is effective when ischemic preconditioning is administered during ischemia (PerC) and before reperfusion and examined the role of the K(+)-dependent ATP (K(ATP)) channel. Twenty 20-kg pigs were randomized (10 in each group) to 40 min of left anterior descending coronary artery occlusion with 120 min of reperfusion. PerC consisted of four 5-min...
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- Publication status:
- Published
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- Publisher copy:
- 10.1152/ajpheart.00617.2006
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Authors
Bibliographic Details
- Journal:
- American journal of physiology. Heart and circulatory physiology
- Volume:
- 292
- Issue:
- 4
- Pages:
- H1883-H1890
- Publication date:
- 2007-04-01
- DOI:
- EISSN:
-
1522-1539
- ISSN:
-
0363-6135
- Source identifiers:
-
105151
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:105151
- UUID:
-
uuid:3c9be6fd-9170-4ab8-919f-d27a5254ca0d
- Local pid:
- pubs:105151
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2007
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