- Abstract:
-
Antibody interaction with a specific epitope of the HLA class I alpha1 domain triggers apoptosis of activated but not resting T and B cells by a pathway which involves neither Fas ligand nor tumor necrosis factor-alpha. We have investigated at which stage of activation and proliferation T cells become sensitive to HLA class I-mediated apoptosis, using two monoclonal antibodies (mAb) which recognize the same monomorphic epitope of the HLA class I alpha1 domain (mAb9O, mouse IgG1, and YTH862, r...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1002/eji.1830270221
-
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- Journal:
- European journal of immunology
- Volume:
- 27
- Issue:
- 2
- Pages:
- 495-499
- Publication date:
- 1997-02-05
- DOI:
- EISSN:
-
1521-4141
- ISSN:
-
0014-2980
- URN:
-
uuid:3c933f52-f4ff-411b-8539-59b60084e4b7
- Source identifiers:
-
12472
- Local pid:
- pubs:12472
- Copyright date:
- 1997
Journal article
T cell sensitivity to HLA class I-mediated apoptosis is dependent on interleukin-2 and interleukin-4.
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