Investigation of the cytoplasmic pool of centriolar and centrosomal proteins

Thesis

How cells control the size and number of their organelles is largely unclear. In the Raff laboratory, we study centriole and centrosome biogenesis to investigate how their assembly is dynamically regulated. Centrioles are barrel-shaped cell organelles that, in preparation for mitosis, can give rise to the centrosome, an amorphous, protein-dense structure. In Drosophila, only a small number of proteins are essential for the formation of both organelles: centrioles require the five core duplica...

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Authors: Steinacker, TL

• Type of award: DPhil
• Level of award: Doctoral
• Awarding institution: University of Oxford
• Language: English
• Keywords: microscopy; centrosome; drosophila; FCS; centriole
• Subjects: Biology