Effects of montelukast compared to double dose budesonide on airway inflammation and asthma control.

Journal article

Many patients with asthma remain symptomatic with impaired airway function on inhaled steroids. This study investigates the relationship between the clinical effect seen in response to additional treatment and the effect on airway inflammatory indices. Seventy-five adult asthmatic patients, incompletely controlled on 800 mcg budesonide/day, were randomised following a 4 week run-in period, to a double-blind, multi-centre controlled clinical trial of doubling inhaled corticosteroid (budesonide...

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Authors: Barnes, N; Laviolette, M; Allen, D; Flood-Page, P; Hargreave, F

• Journal: Respiratory medicine
• Volume: 101
• Issue: 8
• Pages: 1652-1658
• Publication date: 2007-08-01
• DOI: 10.1016/j.rmed.2007.03.007
• EISSN: 1532-3064
• ISSN: 0954-6111
• Language: English
• Keywords: Quinolines; Middle Aged; Adolescent; Aged; Humans; Adult; Sputum; Double-Blind Method; Male; Female; Asthma; Treatment Outcome; Bronchodilator Agents; Administration, Inhalation; Anti-Asthmatic Agents; Acetates; Budesonide