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Vaccinia virus utilizes microtubules for movement to the cell surface.

Abstract:

Vaccinia virus (VV) egress has been studied using confocal, video, and electron microscopy. Previously, intracellular-enveloped virus (IEV) particles were proposed to induce the polymerization of actin tails, which propel IEV particles to the cell surface. However, data presented support an alternative model in which microtubules transport virions to the cell surface and actin tails form beneath cell-associated enveloped virus (CEV) particles at the cell surface. Thus, VV is unique in using b...

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Publication status:
Published

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Publisher copy:
10.1083/jcb.200104124

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Journal:
Journal of cell biology
Volume:
154
Issue:
2
Pages:
389-402
Publication date:
2001-07-01
DOI:
EISSN:
1540-8140
ISSN:
0021-9525
Source identifiers:
10875

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