- Abstract:
-
The hypothermic, growth hormone and corticotrophin (ACTH) responses to the 5-HT1A receptor agonist buspirone (30 mg orally) were measured in 20 unmedicated patients with major depression and 20 healthy controls. Compared with the controls, the hypothermic responses of the depressed patients to buspirone were significantly attenuated, particularly in patients with melancholic depression. In contrast, the responses of growth hormone and ACTH to buspirone were unchanged. The data suggest that ma...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1192/bjp.164.3.372
-
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- Journal:
- The British journal of psychiatry : the journal of mental science
- Volume:
- 164
- Issue:
- 3
- Pages:
- 372-379
- Publication date:
- 1994-03-05
- DOI:
- EISSN:
-
1472-1465
- ISSN:
-
0007-1250
- URN:
-
uuid:3c24778c-b271-4632-bb7e-c6f6d0e76356
- Source identifiers:
-
186008
- Local pid:
- pubs:186008
- Copyright date:
- 1994
Journal article
5-HT1A receptor sensitivity in major depression. A neuroendocrine study with buspirone.
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