Journal article
PlatformTM, a standards-based data custodianship platform for translational medicine research
- Abstract:
- Biomedical informatics has traditionally adopted a linear view of the informatics process (collect, store and analyse) in translational medicine (TM) studies; focusing primarily on the challenges in data integration and analysis. However, a data management challenge presents itself with the new lifecycle view of data emphasized by the recent calls for data re-use, long term data preservation, and data sharing. There is currently a lack of dedicated infrastructure focused on the 'manageability' of the data lifecycle in TM research between data collection and analysis. Current community efforts towards establishing a culture for open science prompt the creation of a data custodianship environment for management of TM data assets to support data reuse and reproducibility of research results. Here we present the development of a lifecycle-based methodology to create a metadata management framework based on community driven standards for standardisation, consolidation and integration of TM research data. Based on this framework, we also present the development of a new platform (PlatformTM) focused on managing the lifecycle for translational research data assets.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 2.5MB, Terms of use)
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- Publisher copy:
- 10.1038/s41597-019-0156-9
Authors
- Journal:
- Scientific Data More from this journal
- Volume:
- 6
- Issue:
- 1
- Article number:
- 149
- Publication date:
- 2019-08-13
- Acceptance date:
- 2019-07-25
- DOI:
- EISSN:
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2052-4463
- Pmid:
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31409798
- Language:
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English
- Keywords:
- Pubs id:
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pubs:1046275
- UUID:
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uuid:3c21c3dd-206f-4054-b6e9-b5c9cc09f3a6
- Local pid:
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pubs:1046275
- Source identifiers:
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1046275
- Deposit date:
-
2019-09-30
Terms of use
- Copyright holder:
- Emam et al
- Copyright date:
- 2019
- Notes:
- Copyright © The Author(s) 2019. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
- Licence:
- CC Attribution (CC BY)
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