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Polyploidy in vertebrate ancestry: Ohno and beyond

Abstract:

Over 30 years ago, Susumu Ohno proposed that two rounds of polyploidy occurred early in vertebrate evolution. We re-examine this proposal using three recent lines of evidence. First, total gene number estimates from completely sequenced genomes suggest an increase in total gene number somewhere along the vertebrate or prevertebrate lineage, compatible with Ohno's model. Second, analyses of homeobox and other genes from amphioxus reveal very extensive gene duplication specifically on the verte...

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Publication status:
Published

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Authors


Furlong, RF More by this author
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Institution:
University of Oxford
Department:
Oxford, MPLS, Zoology
Volume:
82
Issue:
4
Pages:
425-430
Publication date:
2004-08-05
DOI:
EISSN:
1095-8312
ISSN:
0024-4066
URN:
uuid:3bf8c5bb-d63c-4f0a-b651-f3ce08e3b051
Source identifiers:
204411
Local pid:
pubs:204411

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