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Polyploidy in vertebrate ancestry: Ohno and beyond

Abstract:

Over 30 years ago, Susumu Ohno proposed that two rounds of polyploidy occurred early in vertebrate evolution. We re-examine this proposal using three recent lines of evidence. First, total gene number estimates from completely sequenced genomes suggest an increase in total gene number somewhere along the vertebrate or prevertebrate lineage, compatible with Ohno's model. Second, analyses of homeobox and other genes from amphioxus reveal very extensive gene duplication specifically on the verte...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MPLS
Department:
Zoology
Role:
Author
Volume:
82
Issue:
4
Pages:
425-430
Host title:
BIOLOGICAL JOURNAL OF THE LINNEAN SOCIETY
Publication date:
2004-08-01
DOI:
EISSN:
1095-8312
ISSN:
0024-4066
Source identifiers:
204411
Keywords:
Pubs id:
pubs:204411
UUID:
uuid:3bf8c5bb-d63c-4f0a-b651-f3ce08e3b051
Local pid:
pubs:204411
Deposit date:
2012-12-19

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