Journal article
Activation of Salmonella Typhi-specific regulatory T cells in typhoid disease in a wild-type S. Typhi challenge model.
- Abstract:
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Salmonella Typhi (S. Typhi), the causative agent of typhoid fever, causes significant morbidity and mortality worldwide. Currently available vaccines are moderately efficacious, and identification of immunological responses associated with protection or disease will facilitate the development of improved vaccines. We investigated S. Typhi-specific modulation of activation and homing potential of circulating regulatory T cells (Treg) by flow and mass cytometry using specimens obtained from a h...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Version of record, pdf, 905.1KB)
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- Publisher copy:
- 10.1371/journal.ppat.1004914
Authors
Funding
European Union
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Jenner Institute
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Oxford Martin School
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National Institute for Health Research Oxford Biomedical Research Centre
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Bibliographic Details
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS pathogens Journal website
- Volume:
- 11
- Issue:
- 5
- Pages:
- e1004914
- Publication date:
- 2015-01-01
- DOI:
- EISSN:
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1553-7374
- ISSN:
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1553-7366
Item Description
- Language:
- English
- Pubs id:
-
pubs:524807
- UUID:
-
uuid:3bf1196b-8bea-4cf0-9907-37856b8a7cff
- Local pid:
- pubs:524807
- Source identifiers:
-
524807
- Deposit date:
- 2015-11-28
Terms of use
- Copyright holder:
- McArthur et al
- Copyright date:
- 2015
- Notes:
- Copyright © 2015 McArthur et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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