Journal article icon

Journal article

Loci influencing blood pressure identified using a cardiovascular gene-centric array.

Abstract:

Blood pressure (BP) is a heritable determinant of risk for cardiovascular disease (CVD). To investigate genetic associations with systolic BP (SBP), diastolic BP (DBP), mean arterial pressure (MAP) and pulse pressure (PP), we genotyped ∼50 000 single-nucleotide polymorphisms (SNPs) that capture variation in ∼2100 candidate genes for cardiovascular phenotypes in 61 619 individuals of European ancestry from cohort studies in the USA and Europe. We identified novel associations between rs347591 ...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1093/hmg/dds555

Authors


Ganesh, SK More by this author
Tragante, V More by this author
Lanktree, MB More by this author
Expand authors...
Journal:
Human molecular genetics
Volume:
22
Issue:
8
Pages:
1663-1678
Publication date:
2013-04-05
DOI:
EISSN:
1460-2083
ISSN:
0964-6906
URN:
uuid:3be88b5d-3ba0-4af2-a114-39072b29c294
Source identifiers:
374253
Local pid:
pubs:374253

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP