Journal article
Loci influencing blood pressure identified using a cardiovascular gene-centric array.
- Abstract:
-
Blood pressure (BP) is a heritable determinant of risk for cardiovascular disease (CVD). To investigate genetic associations with systolic BP (SBP), diastolic BP (DBP), mean arterial pressure (MAP) and pulse pressure (PP), we genotyped ∼50 000 single-nucleotide polymorphisms (SNPs) that capture variation in ∼2100 candidate genes for cardiovascular phenotypes in 61 619 individuals of European ancestry from cohort studies in the USA and Europe. We identified novel associations between rs347591 ...
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- Publication status:
- Published
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- Publisher copy:
- 10.1093/hmg/dds555
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Authors
Bibliographic Details
- Journal:
- Human molecular genetics
- Volume:
- 22
- Issue:
- 8
- Pages:
- 1663-1678
- Publication date:
- 2013-04-05
- DOI:
- EISSN:
-
1460-2083
- ISSN:
-
0964-6906
- URN:
-
uuid:3be88b5d-3ba0-4af2-a114-39072b29c294
- Source identifiers:
-
374253
- Local pid:
- pubs:374253
Item Description
- Language:
- English
- Keywords:
Terms of use
- Copyright date:
- 2013
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