Journal article
[Glycosphingolipids Gb3 and iGb3. In vivo roles in hemolytic-uremic syndrome and iNKT cell function].
- Abstract:
-
UNLABELLED: The glycosphingolipids globotrihexosylceramide (Gb3, CD77) and isoglobotrihexosylceramide (iGb3) are isomers differing only in one glycosidic bond and have been implicated in several processes of the innate and adaptive immune system. AIMS: 1) To verify the function of Gb3 in the pathogenesis of hemolytic-uremic syndrome as the cellular receptor responsible for cytotoxicity caused by verotoxin (VT) elaborated by Shigella and certain strains of E.coli. 2) To investigate in vivo the...
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- Publisher copy:
- 10.1007/s00292-008-1040-0
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Bibliographic Details
- Journal:
- Der Pathologe
- Volume:
- 29 Suppl 2
- Issue:
- S2
- Pages:
- 297-302
- Publication date:
- 2008-11-05
- DOI:
- EISSN:
-
1432-1963
- ISSN:
-
0172-8113
- URN:
-
uuid:3be0d029-1835-4f82-b536-5c042bc06f18
- Source identifiers:
-
34397
- Local pid:
- pubs:34397
Item Description
Terms of use
- Copyright date:
- 2008
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