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Journal article

Kinetic and mechanistic requirements for helping CD8 T cells.

Abstract:

The requirements for the generation of fully competent long-lived memory CD8 T cells and in particular the role and the mechanisms of help from CD4 T cells remain ill-defined. Memory CD8 T cells generated in the absence of CD4 T cell help often have an impaired recall proliferation and are thus unable to confer protection against certain pathogens. However, the timing and the mechanisms involved in the delivery of help are still unclear and differ between various experimental systems. In this...

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Publication status:
Published

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Publisher copy:
10.4049/jimmunol.180.3.1517

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Jenner Institute
Role:
Author
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Journal:
Journal of immunology (Baltimore, Md. : 1950)
Volume:
180
Issue:
3
Pages:
1517-1525
Publication date:
2008-02-05
DOI:
EISSN:
1550-6606
ISSN:
0022-1767
URN:
uuid:3bdf7357-de15-457d-8c44-77857109b252
Source identifiers:
422424
Local pid:
pubs:422424

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