Journal article
Modeling osteocyte network formation: healthy and cancerous environments
- Abstract:
-
Advanced cancers, such as prostate and breast cancers, commonly metastasize to bone. In the bone matrix, dendritic osteocytes form a spatial network allowing communication between osteocytes and the osteoblasts located on the bone surface. This communication network facilitates coordinated bone remodeling. In the presence of a cancerous microenvironment, the topology of this network changes. In those situations, osteocytes often appear to be either overdifferentiated (i.e., there are more den...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Bibliographic Details
- Publisher:
- Frontiers Media Publisher's website
- Journal:
- Frontiers in Bioengineering and Biotechnology Journal website
- Volume:
- 8
- Article number:
- 757
- Publication date:
- 2020-01-01
- Acceptance date:
- 2020-06-12
- DOI:
- EISSN:
-
2296-4185
- ISSN:
-
2296-4185
- Pmid:
-
32793566
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
1126102
- Local pid:
- pubs:1126102
- Deposit date:
- 2020-09-09
Terms of use
- Copyright holder:
- Taylor-King et al.
- Copyright date:
- 2020
- Rights statement:
- © 2020 Taylor-King, Buenzli, Chapman, Lynch and Basanta. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
- Licence:
- CC Attribution (CC BY)
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