Journal article
Viral macrodomains: Unique mediators of viral replication and pathogenesis.
- Abstract:
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Viruses from the Coronaviridae, Togaviridae, and Hepeviridae families all contain genes that encode a conserved protein domain, called a macrodomain; however, the role of this domain during infection has remained enigmatic. The recent discovery that mammalian macrodomain proteins enzymatically remove ADP-ribose, a common post-translation modification, from proteins has led to an outburst of studies describing both the enzymatic activity and function of viral macrodomains. These new studies h...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
-
-
(Accepted manuscript, pdf, 806.4KB)
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- Publisher copy:
- 10.1016/j.tim.2017.11.011
Authors
Funding
Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Trends in Microbiology Journal website
- Volume:
- 26
- Issue:
- 76
- Pages:
- 598-610
- Publication date:
- 2017-12-18
- Acceptance date:
- 2017-12-18
- DOI:
- EISSN:
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1878-4380
- ISSN:
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0966-842X
- Pmid:
-
29268982
Item Description
- Language:
- English
- Keywords:
- Pubs id:
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pubs:812812
- UUID:
-
uuid:3bd52bd3-0791-4923-85de-47f8e17a9755
- Local pid:
- pubs:812812
- Source identifiers:
-
812812
- Deposit date:
- 2018-01-09
Terms of use
- Copyright holder:
- Elsevier Ltd
- Copyright date:
- 2017
- Notes:
- © 2017 Elsevier Ltd. All rights reserved. This is the accepted manuscript version of the article. The final version is available online from Elsevier at: https://doi.org/10.1016/j.tim.2017.11.011
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