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Reduced cortical excitability in depression. Impaired post-exercise motor facilitation with transcranial magnetic stimulation.

Abstract:

BACKGROUND: In healthy controls, preactivation of muscles by exercise results in enhanced motor-evoked potential (MEP) responses to transcranial magnetic stimulation (TMS). AIMS: We tested the hypothesis that medicated, depressed patients would show reduced post-exercise MEP facilitation compared with controls. METHOD: Ten patients with DSM-IV depression (two male, eight female) and ten controls (three male, seven female) participated. MEPs were elicited at rest, then after exercising the con...

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Publisher copy:
10.1192/bjp.174.5.449

Authors


Shajahan, PM More by this author
Glabus, MF More by this author
Gooding, PA More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
Journal:
The British journal of psychiatry : the journal of mental science
Volume:
174
Issue:
5
Pages:
449-454
Publication date:
1999-05-05
DOI:
EISSN:
1472-1465
ISSN:
0007-1250
URN:
uuid:3baabb5d-e1c3-419a-900f-32a1fdcbe3e8
Source identifiers:
139162
Local pid:
pubs:139162

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