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Interferon as therapy for multiple myeloma: an individual patient data overview of 24 randomized trials and 4012 patients.

Abstract:

Many randomized trials have evaluated alpha-interferon as myeloma therapy, some suggesting a benefit and others not. Most were too small to give reliable answers, so a systematic overview has been performed to provide a more reliable estimate of the effect of interferon. The main end-points were response rates (induction trials), progression-free survival (PFS) and overall survival (OS). Individual patient data were supplied for 24 trials involving 4012 patients, 12 induction trials (2469 pat...

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Publication status:
Published

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Authors


Myeloma Trialists' Collaborative Group More by this author
Journal:
British journal of haematology
Volume:
113
Issue:
4
Pages:
1020-1034
Publication date:
2001-06-05
DOI:
EISSN:
1365-2141
ISSN:
0007-1048
URN:
uuid:3b8782dc-3013-4088-b16f-821e4a75017b
Source identifiers:
37936
Local pid:
pubs:37936

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