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Journal article

Marimastat as maintenance therapy for patients with advanced gastric cancer: a randomised trial.

Abstract:

This randomised, double-blind, placebo-controlled study was designed to evaluate the ability of the orally administered matrix metalloproteinase inhibitor, marimastat, to prolong survival in patients with non-resectable gastric and gastro-oesophageal adenocarcinoma. Three hundred and sixty-nine patients with histological proof of adenocarcinoma, who had received no more than a single regimen of 5-fluorouracil-based chemotherapy, were randomised to receive either marimastat (10 mg b.d.) or pla...

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Publication status:
Published

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Publisher copy:
10.1038/sj.bjc.6600310

Authors


Bramhall, SR More by this author
Hallissey, MT More by this author
Whiting, J More by this author
Scholefield, J More by this author
Tierney, G More by this author
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Journal:
British journal of cancer
Volume:
86
Issue:
12
Pages:
1864-1870
Publication date:
2002-06-05
DOI:
EISSN:
1532-1827
ISSN:
0007-0920
URN:
uuid:3b72edb1-0058-4f3c-b741-02b2a1b8e279
Source identifiers:
70936
Local pid:
pubs:70936

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