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Accuracy of AccessBio Immunoglobulin M and Total Antibody Rapid Immunochromatographic Assays for the Diagnosis of Acute Scrub Typhus Infection.

Abstract:

Using archived samples, we assessed the diagnostic capacity of a rapid immunochromatographic test (ICT) for the detection of Orientia tsutsugamushi IgM and total antibodies to aid with the diagnosis of acute scrub typhus infection in febrile patients in Laos. The sensitivity and the specificity of the ICT for the detection of IgM were 96.8% (121/125 samples; 95% confidence interval [CI], 92.1 to 99.1%) and 93.3% (98/105 samples; 95% CI, 86.7 to 97.3%), respectively. For the detection of total...

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Publication status:
Published

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Publisher copy:
10.1128/cvi.00448-08

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Author
Journal:
Clinical and vaccine immunology : CVI
Volume:
17
Issue:
2
Pages:
263-266
Publication date:
2010-02-01
DOI:
EISSN:
1556-679X
ISSN:
1556-6811
Language:
English
Keywords:
Pubs id:
pubs:17027
UUID:
uuid:3b6bdcbe-d9b4-4bba-a62b-37463252c37b
Local pid:
pubs:17027
Source identifiers:
17027
Deposit date:
2012-12-19

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