Journal article
Continuous and discontinuous changes in the unit cell of HIV-1 reverse transcriptase crystals on dehydration.
- Abstract:
-
A crystal form of HIV-1 reverse transcriptase (RT) complexed with inhibitors showed diffraction to a high-resolution limit of 3.7 A. Instability in the unit-cell dimensions of these crystals was observed during soaking experiments, but the range of this variability and consequent change in lattice order was revealed by a chance observation of dehydration. Deliberately induced dehydration results in crystals having a variety of unit cells, the best-ordered of which show diffraction to a minimu...
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- Publication status:
- Published
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Bibliographic Details
- Journal:
- Acta crystallographica. Section D, Biological crystallography
- Volume:
- 54
- Issue:
- Pt 5
- Pages:
- 938-953
- Publication date:
- 1998-09-01
- DOI:
- EISSN:
-
1399-0047
- ISSN:
-
0907-4449
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:21343
- UUID:
-
uuid:3b6887dd-e340-446f-9009-24a8eb69f44e
- Local pid:
- pubs:21343
- Source identifiers:
-
21343
- Deposit date:
- 2012-12-19
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- Copyright date:
- 1998
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